All Publications:
https://scholar.google.com/citations?hl=en&user=x1V6G-gAAAAJ
Selected
Publications:
1.
Liao,
M.†, Liu, Y.†, Xu, Z.†, Fang, M., Yu, Z., Cui, Y., Sun, Z., Huo, R., Yang, J.,
Huang, F., Liu, M., Zhou, Q., Song, X., Han, H., Chen, S., Xu, X., Qin, X., He,
Q., Ju, D., Wang, T., Thakkar, N., Hardin, P.E., Golden, S.S., and Zhang,
E.E.* The P-loop NTPase RUVBL2 is a conserved clock component across
eukaryotes. Nature, 642:165–173 (2025)
2.
Yu,
Z., Ran, G., Chai, J., and Zhang, E.E.* A nature-inspired HIF stabilizer
derived from a highland-adaptation insertion of plateau pika Epas1 protein. Cell
Reports, 43:114727 (2024)
3.
Sang,
D.†, Lin, K.†, Yang, Y.†, Ran, G., Li, B., Chen, C., Li, Q., Ma, Y., Lu, L.,
Cui, X.-Y., Liu, Z., Lv, S.-Q., Luo, M., Liu, Q., Li, Y., and Zhang, E.E.*
Prolonged sleep deprivation induces a cytokine storm-like syndrome in mammals.
(2023) Cell 186: 5500-5516 {Highlighted by Nature Reviews Immunology:
“Sleep deprivation whips up cytokine storm”; Featured by Cell “Best papers of
2024”}
4.
Yu,
Z., and Zhang, E.E.* Disrupted circadian rhythms in the plateau pika.
(2023) Trends in Neurosciences 46: 1005-1007
5.
Jiang,
W.†*, Jin, L.†, Ju, D.†, Lu, Z.†, Wang, C., Guo, X., Zhao, H., Shen, S., Cheng,
Z., Shen, J., Zong, G., Chen, J., Li, K., Yang, L., Zhang, Z., Feng, Y., Shen,
J.Z., Zhang, E.E.*, and Wan, R.* The pancreatic clock is a key
determinant of pancreatic fibrosis progression and exocrine dysfunction. (2022) Science
Translational Medicine 14: eabn3586 {Highlighted by Nature
Reviews Gastroenterology & Hepatology: “Stopped clock promotes
fibrosis in chronic pancreatitis”}
6.
Liu,
N.†, Tian, H.†, Yu, Z.†, Zhao, H.†, Li, W.†, Sang, D., Lin, K., Cui, Y., Liao,
M., Xu, Z., Chen, C., Guo, Y., Wang, Y., Huang, H-w, Wang, J., Zhang, H., Wu,
W., Huang, H., Lv, S., Guo, Z., Wang, W., Zheng, S., Wang, F., Zhang, Y.*, Cai,
T.*, and Zhang, E.E.* A highland-adaptation mutation of the Epas1
protein increases its stability and disrupts the circadian clock in the plateau
pika. (2022) Cell Reports 39: 110816
7.
Ju,
D.†, Zhang, W.†, Yan, J., Zhao, H., Li, W., Wang, J., Liao, M., Xu, Z., Wang,
Z., Zhou, G., Mei, L., Hou, N., Ying, S., Cai, T., Chen, S., Xie, X., Lai, L.,
Tang, C., Park, N., Takahashi, J.S., Huang, N., Qi, X.*, and Zhang, E.E.*
Chemical Perturbations Reveal That RUVBL2 Regulates the Circadian Phase in
Mammals. (2020) Science Translational Medicine 12: eaba0769 {Featured by Editor
in the issue: “Shifting clock gears”; and by Nature Reviews Drug Discovery:
“Shortening jet-lag recovery”; Highlighted by Faculty of 1000 (Very
Good)}
8.
Peng,
S.†, Xiao, W.†, Ju, D.†, Sun, B., Hou, N., Liu, Q., Wang, Y., Zhao, H., Gao,
C., Zhang, S., Cao, R., Li, P., Huang, H., Ma, Y., Wang, Y., Lai, W., Ma, Z.,
Zhang, W., Huang, S., Wang, H., Zhang, Z., Zhao, L., Cai, T., Zhao, Y., Wang,
F., Nie, Y., Zhi, G., Yang, Y.*, Zhang, E.E.*, and Huang, N.*
Identification of Entacapone as a Chemical Inhibitor of FTO Mediating Metabolic
Regulation Through FOXO1. (2019) Science Translational Medicine 11:
eaau7116 {Featured by Editor in the issue: “The skinny on FTO”}
9.
Mei,
L., Fan, Y., Lv, X., Welsh, D.K., Zhan, C.*, and Zhang, E.E.* Long-term
in vivo Recording of Circadian Rhythms in Brains of Freely Moving Mice. (2018) Proceedings
of the National Academy of Sciences U.S.A. 115: 4276-4281 {Highlighted
by Faculty
of 1000 (Very Good)}
10.
Wu,
Y.†, Tang, D.†, Liu, N., Xiong, W., Huang, H., Li, Y., Ma, Z., Zhao, H., Chen,
P., Qi, X., and Zhang, E.E.* Reciprocal Regulation between the Circadian
Clock and Hypoxia Signaling at the Genome Level in Mammals. (2017) Cell
Metabolism 25: 73-85 {Cover story of the issue; Featured by Science
Signaling, “Daily oxygen rhythms”}
专利 Awarded Patents:
1. Zhang,
E., Qi, X.,
Ju, D., Zhou, G., Zhao, H., Mei, L., Wang, Z., and Liang, L. Nucleoside
analogue regulating mammalian circadian rhythm. WIPO Publication #
WO2018133835A1 (granted in China and Japan; pending in USA, European Union,
etc; PCT priority date: 02.02.2017)
2. Zhang,
E., Zhan, C.,
and Mei, L. A method and instrumental design for long-term and real-time
recording of gene transcriptions in live animals. NIPA Application#
2017101661043 (granted in China)
受邀报告 Invited Talks in
Conferences:
1.
19th
ITMAT Annual International Symposium, University of Pennsylvania, Philadelphia,
USA, October 2024
2.
Cold
Spring Harbor Laboratory-Asia Conference on Sleep Mechanism & Function,
Suzhou, CHINA, September 2024
3.
7th
Asian Forum on Chronobiology, Sapporo, JAPAN, August 2024 (Keynote Speaker)
4.
Society
for Research on Biological Rhythms Biennial Meeting, Puerto Rico, May 2024
5.
Annual
Meeting of China Sleep Research Society, Hefei, CHINA, October 2023 (Keynote
Speaker)
6.
International
Symposium on Circadian Rhythms in Sleep, Physiology, and Medicine, Chongqing,
CHINA, October 2023 (Co-organizer)
7.
Society
for Research on Biological Rhythms Biennial Meeting, Amelia Island, Florida,
USA, May 2022 (Program Committee, Session Chair)
8.
Society
for Research on Biological Rhythms Biennial Meeting, Virtual Conference, USA,
June 2020
9.
Center
for Circadian Biology Annual Meeting, University of California San Diego, USA,
March 2020
10.
Keystone
Symposia on "Hypoxia: Molecules, Mechanisms and Disease",
Keystone, Colorado, USA, January 2020 (Session Chair)
11.
XVI
Congress, European Biological Rhythm Society, Lyon, FRANCE, August 2019
12.
5th
World Congress of Chronobiology, Suzhou, CHINA, April
2019 (Co-organizer)
13.
1st
Beijing International Symposium on the Circadian Clock and Sleep Research,
Beijing, CHINA, April 2019 (Co-organizer)
14.
Sapporo
Symposium on Biological Rhythms, Japanese Society for Chronobiology,
Sapporo, JAPAN, July 2018
15.
Society
for Research on Biological Rhythms Biennial Meeting, Amelia Island,
Florida, USA, May 2018
16.
Gordon
Research Conference on Chronobiology, Stowe, Vermont, USA, July 2017
17.
2nd
Asian Forum on Chronobiology, Hohhot, Inner Mongolia, CHINA,
June 2017 (Co-organizer)
18.
International
ChronoBiology Summer School, Peking University, Beijing, CHINA, August 2016
(Co-organizer)