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实验室

14:00-15:00, Monday, April 15, 2019


Speaker: Dan Sikkema, Ph.D.

Vice President, Accelerator

Services, Quanterix Corp. USA

Topic: Quanterix SIMOA solutions for Biomarkers, PK, and Immunogenicity to Accelerate Drug Development

Host:  Weiliang Fan, Ph.D.

Abstract

Simoa (single molecule assay) is a technology that allows ultrasensitive detection of bio-molecular in a variety of research scenarios. It can measure protein at level as low as fg/ml. It is becoming a promising tool in the fields of both basic and clinical researches. For instance, a recent article published in the journal Nature Medicine (PMID: 30664784) demonstrated that neuronal damage in Alzheimer’s patients could be detected—via measuring neurofilament light chain (NfL) in human serum using Simoa—more than 16 years before the onset of cognition decline, the traditional method applied in AD diagnosis. Quanterix is a bio-tech company who has transferred this technology into a fully automatic research instrument.