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Original Research Articles

Chi H, Chen H, He k, Wu l, Yang B, Sun RX, Liu J, Zeng WF, Song CQ, He SM, and Dong MQ

pNovo+: De Novo Peptide Sequencing Using Complementary HCD and ETD Tandem Mass Spectra

Journal of Proteome Research, doi.org/10.1021/pr3006843, Dec. 28, 2012 Article

Wang G, Wang X, Yu H, Wei S, Williams N, Holmes DL, Halfmann R, Naidoo J, Wang L, Li L, Chen S, Harran P, Lei X & Wang X

Small-molecule activation of the TRAIL receptor DR5 in human cancer cells

Nature Chemical Biology, doi: 10.1038/nchembio.1153, Dec. 27, 2012 Article

Yao Q, Cui J, Wang J, Li T, Wan X, Luo T, Gong Y, Xu Y, Huang N, and Shao F

Structural mechanism of ubiquitin and NEDD8 deamidation catalyzed by bacterial effectors that induce macrophage-specific apoptosis

Proc. Natl. Acad. Sci. USA, doi/10.1073/pnas.1210831109, Dec. 11, 2012 Article

Zhou Z, Zhang MJ, Peng X, Takayama Y, Xu XY, Huang LZ, and Du LL

Mapping genomic hotspots of DNA damage by a single-strand-DNA-compatible and strand-specific ChIP-seq method

Genome Research, doi:10.1101/gr.146357.112, Dec. 17, 2012 Article

Huang J, Wang H, Chen Y, Wang X and Zhang H

Residual body removal during spermatogenesis in C. elegans requires genes that mediate cell corpse clearance

Development, doi:10.1242/dev.086769, Dec. 3, 2012 Article

Yan H, Zhong G, Xu G, He W, Jing Z, Gao Z, Huang Y, Qi Y, Peng B, Wang H, Fu L, Song M, Chen P, Gao W, Ren B, Sun Y, Cai T, Feng X, Sui J, Li W

Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus

eLife, 2012;1:e00049. DOI: 10.7554/eLife.00049, Nov. 15, 2012 Article

Yang N, Wang W, Wang Y, Wang M, Zhao Q, Rao Z, Zhu B, and Xu R

Distinct mode of methylated lysine-4 of histone H3 recognition by tandem tudor-like domains of Spindlin1

Proc. Natl. Acad. Sci. USA, doi/10.1073/pnas.1208517109, Oct. 17, 2012 Article

Zhou C, Huang H, Kim SM, Lin H, Meng X, Han KA, Chiang AS, Wang JW, Jiao R, and Rao Y

Molecular Genetic Analysis of Sexual Rejection: Roles of Octopamine and Its Receptor OAMB in Drosophila Courtship Conditioning

Journal of Neuroscience, DOI:10.1523/JNEUROSCI.0517-12.2012, Oct. 10, 2012 Article

Li H, Wang X, Hong B, and Lei X

Collective Synthesis of Lycopodium Alkaloids and Tautomer Locking Strategy for the Total Synthesis of (?)-Lycojapodine A

The Journal of Organic Chemistry, Oct. 15, 2012 Article

Hu F, Ren J, Zhang J, Zhong W, and Luo M

Natriuretic peptides block synaptic transmission by activating phosphodiesterase 2A and reducing presynaptic PKA activity

Proc. Natl. Acad. Sci. USA, doi/10.1073/pnas.1209185109, Oct. 8, 2012 Article

Jin W, Niu Z, Xu D, Li X

RBM5 promotes exon 4 skipping of AID pre-mRNA by competing with the binding of U2AF65 to the polypyrimidine tract

FEBS Letters, Sep. 24, 2012 Article

Zheng S, Wang J, Feng Y, Wang J and Ye K

Solution structure of MSL2 CXC domain reveals an unusual Zn3Cys9 cluster and similarity to pre-SET domains of histone lysine methyltransferases.

PLoS ONE, doi: 10.1371/journal.pone.0045437, Sep. 20, 2012 Article

Dong N, Zhu Y, Lu Q, Hu L, Zheng Y, and Shao F

Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses

Cell, doi.org/10.1016/j.cell.2012.06.050, Aug. 31, 2012 Article

Yang X, Duan J, Li S, Wang P, Ma S, Ye K and Zhao XS

Kinetic and thermodynamic characterization of the reaction pathway of box H/ACA RNA-guided pseudouridine formation

Nucleic Acids Res, doi: 10.1093/nar/gks882, Aug. 30, 2012 Article

Yuan W, Wu T, Fu H, Dai C, Wu H, Liu N, Li X, Xu M, Zhang Z, Niu T, Han Z, Chai J, Zhou XJ, Gao S, Zhu B

Dense Chromatin Activates Polycomb Repressive Complex 2 to Regulate H3 Lysine 27 Methylation

Science, DOI: 10.1126/science.1225237, Aug. 24, 2012 Article

Liang Q, Yang P, Tian E, Han J and Zhang H

The C. elegans ATG101 homolog EPG-9 directly interacts with EPG-1/Atg13 and is essential for autophagy

Autophagy, Jul. 20, -2012 Article

Ma M and Luo M

Optogenetic Activation of Basal Forebrain Cholinergic Neurons Modulates Neuronal Excitability and Sensory Responses in the Main Olfactory Bulb

The Journal of Neuroscience, DOI:10.1523/JNEUROSCI.0058-12.2012, Jul. 25, 2012 Article

Liu B, Du H, Rutkowski R, Gartner A, Wang X

LAAT-1 Is the Lysosomal Lysine/Arginine Transporter That Maintains Amino Acid Homeostasis

Science, DOI: 10.1126/science.1220281, Jul. 20, 2012 Article

Li C, Dian L, Zhang W, and Lei X

Biomimetic Syntheses of (-)-Gochnatiolides A-C and (-)-Ainsliadimer B

J. Am. Chem. Soc., doi.org/10.1021/ja305464s, Jul. 19, 2012 Article

Qu M, Yang B, Tao L, Yates III JR, Russell P, Dong MQ, Du LL

Phosphorylation-Dependent Interactions between Crb2 and Chk1 Are Essential for DNA Damage Checkpoint

PLoS Genetics, doi:10.1371/journal.pgen.1002817, Jul. 5, 2012 Article

Wu F, Li Y, Wang F, Noda NN and Zhang H

Differential function of the two Atg4 homologues in the aggrephagy pathway in C. elegans

Journal of Biological Chemistry, doi/10.1074/jbc.M112.365676, Jul. 5, 2012 Article

Yang B, Wu YJ, Zhu M, Fan SB, Lin J, Zhang K, Li S, Chi H, Li YX, Chen HF, Luo SK, Ding YH, Wang LH, Hao Z, Xiu LY, Chen S, Ye K, He SM& Dong MQ

Identification of Cross-linked Peptides from Complex Samples

Nature Methods, doi:10.1038/nmeth.2099, Jul. 8, 2012 Article

Zhang Y, Wang H, Kage-Nakadai E, Mitani S, and Wang X

C. elegans Secreted Lipid-Binding Protein NRF-5 Mediates PS Appearance on Phagocytes for Cell Corpse Engulfment

Current Biology, doi.org/10.1016/j.cub.2012.06.004, Jun 21, 2012 Article

Kang Y, Zhao D, Liang H, Liu B, Zhang Y, Liu Q, Wang X, and Liu Y

Structural Study of TTR-52 Reveals the Functional Mechanisms of a Bridging Molecule in Apoptotic Cell Engulfment

Genes & Development, doi:10.1101/gad.187815.112, Jun 15, 2012 Article

Liu T, Liu Z, Song C, Hu Y, Han Z, She J, Fan F, Wang J, Jin C, Chang J, Zhou JM, Chai J

Chitin-Induced Dimerization Activates a Plant Immune Receptor

Science, DOI: 10.1126/science.1218867, Jun 1, 2012 Article

Kong Q, Qu N, Gao M, Zhang Z, Ding X, Yang F, Li Y, Dong OX, Chen S, Li X, and Zhang Y

The MEKK1-MKK1/MKK2-MPK4 Kinase Cascade Negatively Regulates Immunity Mediated by a Mitogen-Activated Protein Kinase Kinase Kinase in Arabidopsis

The Plant Cell, doi/10.1105/tpc.112.097253, May 29, 2012 Article

Ye R, Wang W, Iki T, Liu C, Wu Y, Ishikawa M, Zhou X, and Qi Y

Cytoplasmic Assembly and Selective Nuclear Import of Arabidopsis ARGONAUTE4/siRNA Complexes

Molecular Cell, DOI 10.1016/j.molcel.2012.04.013, May 17, 2012 Article

Zhang CJ, Ning YQ, Zhang SW, Chen Q, Shao CR, Guo YW, Zhou JX, Li L, Chen S, He XJ

IDN2 and Its Paralogs Form a Complex Required for RNA-Directed DNA Methylation

PLoS Genetics, doi:10.1371/journal.pgen.1002693, May 3, 2012 Article

Ge J, Gong YN, Xu Y, and Shao F

Preventing bacterial DNA release and absent in melanoma 2 inflammasome activation by a Legionella effector functioning in membrane trafficking

Proc. Natl. Acad. Sci. USA, doi/10.1073/pnas.1117490109, Apr. 17, 2012 Article

Feng F, Yang F, Rong W, Wu X, Zhang J, Chen S, He C and Zhou JM

A Xanthomonas uridine 5’-monophosphate transferase inhibits plant immune kinases

Nature, doi:10.1038/nature10962, Apr. 15, 2012 Article

Li W, Zou W, Yang Y, Chai Y, Chen B, Cheng S, Tian D, Wang X, Vale RD, and Ou G

Autophagy genes function sequentially to promote apoptotic cell corpse degradation in the engulfing cell

The Journal of Cell Biology, doi/10.1083/jcb.201111053, Apr. 2, 2012 Article

Wei W, Ba Z, Gao M, Wu Y, Ma Y, Amiard S, White C, Danielsen J, Yang YG, and Qi Y

A Role for Small RNAs in DNA Double-Strand Break Repair

Cell, DOI 10.1016/j.cell.2012.03.002, Mar. 22, 2012 Article

Niu Z, Jin W, Zhang L and Li X

Tumor suppressor RBM5 directly interacts with the DExD/H-box protein DHX15 and stimulates its helicase activity

FEBS Letters, doi:10.1016/j.febslet.2012.02.052, Mar. 17, 2012 Article

Zhang Z, Wu Y, Gao M, Zhang J, Kong Q, Liu Y, Ba H, Zhou J, and Zhang Y

Disruption of PAMP-Induced MAP Kinase Cascade by a Pseudomonas syringae Effector Activates Plant Immunity Mediated by the NB-LRR Protein SUMM2

Cell Host & Microbe, DOI 10.1016/j.chom.2012.01.015, Mar. 15 2012 Article

Chen P, Song Z, Qi Y, Feng X, Xu N, Sun Y, Wu X, Yao X, Mao Q, Li X, Dong W, Wan X, Huang N, Shen X, Liang Z, and Li W

Molecular Determinants of Enterovirus 71 Viral Entry: Cleft around Gln-172 on VP1 protein interacts with Variable region on Scavenge Receptor B2

Journal of Biological Chemistry, DOI 10.1074/jbc.M111.301622, Feb. 24 2012 Article

Zhang W, Zhao Y, Guo Y and Ye K

The plant actin-binding protein SCAB1 is a dimeric actin crosslinker with an atypical Pleckstrin homology domain

Journal of Biological Chemistry, Feb. 22, 2012 Article

Wang Y, Zheng CG, Jiang Y, Zhang J, Chen J, Yao C, Zhao Q, Liu S, Chen K, Du J, Yang Z, Gao S

Genetic correction of β-thalassemia patient-specific iPS cells and its use in improving hemoglobin production in irradiated SCID mice

Cell Research, doi:10.1038/cr.2012.23, Feb. 7, 2012 Article

Sun L, Wang H, Wang Z, He S, Chen S, Liao D, Wang L, Yan J, Liu W, Lei X, and Wang X

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

Cell, DOI 10.1016/j.cell.2011.11.031, Jan. 19, 2012 Article

Wang Z, Jiang H, Chen S, Du F, and Wang X

The Mitochondrial Phosphatase PGAM5 Functions at the Convergence Point of Multiple Necrotic Death Pathways

Cell, DOI 10.1016/j.cell.2011.11.030, Jan. 19, 2012 Article

Zhao Y, Sun W, Zhang P, Chi H, Zhang MJ, Song CQ, Ma X, Shang Y, Wang B, Hu Y, Hao Z, Hühmer AF, Meng F, L’Hernault SW, He SM, Dong MQ, and Miao L

Nematode sperm maturation triggered by protease involves sperm-secreted serine protease inhibitor (Serpin)

Proc. Natl. Acad. Sci. USA, doi/10.1073/pnas.1109912109, Jan. 17, 2012 Article

Liu J, Luo S, Zhao H, Liao J, Li J, Yang C, Xu B, Stern DF, Xu X and Ye K

Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain

Nucleic Acids Research, doi:10.1093/nar/gkr1296, Jan. 10, 2012 Article