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2015

Original Research Articles

 

Xu Z, Wang W, Jiang K, Yu Z, Huang H, Wang F, Zhou B, Chen T

Embryonic attenuated Wnt/β-catenin signaling defines niche location and long-term stem cell fate in hair follicle.

eLife, DOI: http://dx.doi.org/10.7554/eLife.10567 Dec. 14, 2015 Article

Xu N, Fang W, Mu L, Tang Y, Gao L, Ren S, Cao D, Zhou L, Zhang A, Liu D, Zhou C, Wong K, Yu L, Zhang L, Chen L

Overexpression of wildtype EGFR is tumorigenic and denotes a therapeutic target in non-small cell lung cancer.

Oncotarget, DOI: 10.18632/oncotarget.6461. Dec. 4, 2015 Article

Zhang H, Zhan C, Ke J, Xue Z, Zhang A, Xu K, Shen Z, Yu L, Chen L

EGFR Kinase domain mutation positive lung cancers are sensitive to intrapleural perfusion with hyperthermic chemotherapy (IPHC) complete treatment,

Oncotarget, DOI: 10.18632/oncotarget.6491. Dec. 8, 2015 Article

Hu W, Suo F, Du LL.

Bulk Segregant Analysis Reveals the Genetic Basis of a Natural Trait Variation in Fission Yeast.

Genome Biol Evol. DOI: 10.1093/gbe/evv238. Nov. 27, 2015 Article

Gao L, Jiang Y, Mu L, Liu Y, Wang F, Wang P, Zhang A, Tang N, Chen T, Luo M, Yu L, Gao S, Chen L

Efficient Generation of Mice with Consistent Transgene Expression by FEEST

Sci Rep. DOI: 10.1038/srep16284. Nov. 17, 2015 Article

Liu ZH, Hu JL, Liang JZ, Zhou AJ, Li MZ, Yan SM, Zhang X, Gao S, Chen L, Zhong Q, Zeng MS

Far upstream element-binding protein 1 is a prognostic biomarker and promotes nasopharyngeal carcinoma progression.

Cell Death Dis. DOI: 10.1038/cddis.2015.258. Oct. 15, 2015 Article

Wu H, Wang A, Zhang W, Wang B, Chen C, Wang W, Hu C, Ye Z, Zhao Z, Wang L, Li X, Yu K, Liu J, Wu J, Yan X, Zhao P, Wang J, Wang C, Weisberg E, Gray N, Yun C, Liu J, Chen L, Liu Q

Ibrutinib selectively and irreversibly targets EGFR (L858R, Del19) mutant but is moderately resistant to EGFR (T790M) mutant NSCLC Cells.

Oncotarget, DOI: 10.18632/oncotarget.5182. Oct. 13, 2015 Article

Wang C, Guo X, Dou K, Chen H, Xi R

Ttk69 acts as a master repressor of enteroendocrine cell specification in Drosophila intestinal stem cell lineages

Development, DOI: 10.1242/dev.123208. Aug.10, 2015 Article

Shi J, Zhao Y, Wang K, Shi X, Wang Y, Huang H, Zhuang Y, Cai T, Wang F & Shao F

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

Nature, DOI:10.1038/nature15514. Sep.16, 2015 Article

Liu XM, Sun LL, Hu W, Ding YH, Dong MQ, Du LL

ESCRTs Cooperate with a Selective Autophagy Receptor to Mediate Vacuolar Targeting of Soluble Cargos

Molecular Cell, DOI: 10.1016/j.molcel.2015.07.034Sep. 10, 2015 Article

Hu Z, Hu Y, Liu X, Xi R, Zhang A, Liu D, Xie Q and Chen L

Tumor driven by gain-of-function HER2 H878Y mutant is highly sensitive to HER2 inhibitor

Oncotaget, DOI: 10.18632/oncotarget.5221. Oct. 13, 2015 Article

Luo S, Xin X, Du LL, Ye K, Wei Y

Dimerization Mediated by a Divergent Forkhead-associated Domain Is Essential for the DNA Damage and Spindle Functions of Fission Yeast Mdb1.

J Biol Chem, DOI: 10.1074/jbc.M115.642538. Aug. 21, 2015 Article

Cheng S, Wang K, Zou W, Miao R, Huang Y, Wang H, and Wang X

PtdIns(4,5)P2 and PtdIns3P coordinate to regulate phagosomal sealing for apoptotic cell clearance

The Journal of Cell Biology, DOI: 10.1083/jcb.201501038. Aug. 3, 2015 Article

Zhang H, Cao J, Li L, Liu Y, Zhao H, Li N, Li B, Zhang A, Huang H, Chen S, Dong M, Yu L, Zhang J, Chen L

Identification of urine protein biomarkers with the potential for early detection of lung cancer.

Sci Rep, DOI: 10.1038/srep11805. Jul. 2, 2015 Article

Yang F, Zhao R, Fang X, Huang H, Xuan Y, Ma Y, Chen H, Cai T, Qi Y and Xi R

The RNA surveillance complex Pelo-Hbs1 is required for transposon silencing in theDrosophilagermline

EMBO reports, DOI: 10.15252/embr.201540084. Jun. 29, 2015 Article

Zhu M, Wu G, Li YX, Stevens JK, Fan CX, Spang A, Dong MQ

Serum- and Glucocorticoid-Inducible Kinase-1 (SGK-1) Plays a Role in Membrane Trafficking in Caenorhabditis elegans

PLOS ONE, DOI: 10.1371/journal.pone.0130778, Jun. 26, 2015 Article

Li TM, Liu W, Lu S, Zhang YP, Jia LM, Chen J,  Li X, Lei X, and Dong MQ

No Significant Increase in the Δ4- and Δ7-Dafachronic Acid Concentration in the Long-Lived glp-1 Mutant, nor in the Mutants Defective in Dauer Formation

G3,Genes Genomes Genetics, DOI: 10.1534/g3.115.018812, May 12, 2015 Article

He W, Ren B, Mao F, Jing Z, Li Y, Liu Y, Peng B, Yan H, Qi Y, Sun Y, Guo JT, Sui J, Wang F, Li W

Hepatitis D Virus Infection of Mice Expressing Human Sodium Taurocholate Cotransporting Polypeptide
PLOS Pathogens, DOI:10.1371/journal.ppat.1004840, Apr. 22, 2015
Article

Hu Z, Wan X, Hao R, Zhang H, Li L, Li L, Xie Q, Wang P, Gao Y, Chen S, Wei M, Luan Z, Zhang A, Huang N, Chen L

Phosphorylation of Mutationally Introduced Tyrosine in the Activation Loop of HER2 Confers Gain-of-Function Activity.

PLoS One, DOI: 10.1371/journal.pone.0123623. Apr. 8, 2015 Article

Li D, Xu T, Cao Y, Wang H, Li L, Chen S, Wang X, Shen Z

A cytosolic heat shock protein 90 and cochaperone CDC37 complex is required for RIP3 activation during necroptosis.

Proc Natl Acad Sci U S A, DOI: 10.1073/pnas.1505244112, Apr. 7, 2015 Article

Guo Q, Wang D,He X, Feng Q, Lin R, Xu F, Fu L, Luo M

Whole-brain mapping of inputs to projection neurons and cholinergic interneurons in the dorsal striatum.

PLOS One, DOI: 10.1371/journal.pone.0123381. Apr. 1, 2015 Article

Wang D, He X, Zhao Z, Feng Q, Lin R, Sun Y, Ding T, Xu F, Luo M, Zhan C

Whole-brain mapping of the direct inputs and axonal projections of pro-opiomelanocortin (POMC) and agouti-related peptide (AgRP) neurons.

Front. Neuroanat, DOI 10.3389/fnana.2015.00040, Mar. 27, 2015 Article

Dong T, Li C, Wang X, Dian L, Zhang X, Li L, Chen S, Cao R, Li L, Huang N, He S, Lei X

Ainsliadimer A selectively inhibits IKKα/β by covalently binding a conserved cysteine.

Nat Commun, DOI: 10.1038/ncomms7522, Mar. 27, 2015 Article

Zhu G, Fan Z, Ding M, Zhang H, Mu L, Ding Y, Zhang Y, Jia B, Chen L, Chang Z, Wu W

An EGFR/PI3K/AKT axis promotes accumulation of the Rac1-GEF Tiam1 that is critical in EGFR-driven tumorigenesis.

Oncogene, DOI: 10.1038/onc.2015.45, Mar. 9, 2015 Article

Zhou J, Jia C, Feng Q, Bao J, and Luo M

Prospective Coding of Dorsal Raphe Reward Signals by the Orbitofrontal Cortex

The Journal of Neuroscience, DOI: 10.1523/JNEUROSCI, Feb. 11, 2015 Article

Lu S, Fan SB, Yang B, Li YX, Meng JM, Wu L, Li P, Zhang K, Zhang MJ, Fu Y, Luo J, Sun RX,He SM & Dong MQ

Mapping native disulfide bonds at a proteome scale

Nature Methods, DOI:10.1038/nmeth.3283, Feb. 9, 2015 Article

Zhou Y and Huang N

Binding site druggability assessment in fragment-based drug design.

Methods Mol. Biol, DOI: 10.1007/978-1-4939-2486-8_2 ,Feb.9, 2015 Article

Liu N, Zhang Z, Wu H, Jiang Y, Meng L, Xiong J, Zhao Z, Zhou X, Li J, Li H, Zheng Y, Chen S, Cai T, Gao S, and Zhu B

Recognition of H3K9 methylation by GLP is required for efficient establishment of H3K9 methylation, rapid target gene repression and mouse viability

Genes and Development, DOI:/10.1101/gad.254425.114, Jan. 30, 2015 Article

Zhao HQ, Zhang P, Gao H, He X, Dou Y, Huang AY, Liu X, Ye AY, Dong MQ, Wei L

Profiling the RNA editomes of wild-type C. elegans and ADAR mutants.

Genome Res. DOI:10.1101/gr.176107.114, Jan. 19, 2015 Article

Ning YQ, Ma ZY, Huang HW, Mo H, Zhao TT, Li L, Cai T, Chen S, Ma L and He XJ

Two novel NAC transcription factors regulate gene expression and flowering time by associating with the histone demethylase JMJ14

Nucl. Acids Res. DOI: 10.1093/nar/gku1382, Jan. 10, 2015 Article

Reviews:

Yan H, Liu Y, Sui J, Li W

NTCP opens the door for hepatitis B virus infection

Antiviral Research , DOI :10.1016/j.antiviral, Jun. 2, 2015 Article