郭岩 博士

北京生命科学研究所研究员

Yan Guo, Ph.D.

Assistant Investigator, NIBS, Beijing

教育经历

Education:

1999年 德国科隆大学遗传学系、科隆马普植物育种所博士

Ph.D. Plant Genetics and Molecular Biology, Max-Planck-Institute for Plant Breeding, Cologne, and Department of Genetics,University of Cologne, Germany

1988年 北京农业大学农学系学士

B.S. Plant Breeding, Department of Agronomy, BeijingAgricultural University, China

工作经历

Professional Experience

2004 -2011年 北京生命科学研究所研究员

Assistant Investigator, National Institute of Biological Sciences, Beijing, China  

1999-2003年 美国亚利桑那大学植物科学系博士后

Postdoctoral Research Associate, Department of Plant Sciences,University of Arizona, Tucson, Arizona, USA

1995-1999年 德国科隆大学遗传学系、科隆马普植物育种所博士

Ph.D. Max-Planck-Institute for Plant Breeding, Cologne, and Department of Genetics, University of Cologne, Germany

1988-1995年 中国科学院遗传所研究助理

Research Assistant and Associate, Institute of Genetics, ChineseAcademy of Sciences, Beijing, China   

研究概述

Research Description

我们实验室的研究兴趣主要是植物如何感受并响应环境胁迫，诸如土壤高浓度盐、碱，及干旱，特别是植物在胁迫条件下体内Ca²⁺信号和pH内平衡的调节。

实验室的主要研究内容是利用拟南芥突变体研究植物感受环境胁迫信号过程中所发生的遗传和分子特性的变化。目的是为了阐明植物响应环境胁迫的信号路径，并鉴定一些具有潜在功能的能够提高作物适应环境胁迫的关键作用元件。

Our lab is interested in studying how plants sense and respond to environmental stresses such as high soil salinity, alkalinity and drought. Particularly, we are interested in understanding regulation of Ca²⁺ signaling and pH homeostasis under these stresses in plants.

Our researches focus on genetic and molecular characterization of Arabidopsis mutants that are altered in response to environmental stimuli. The goals are to elucidate the plant signaling pathways in response to environmental stresses and to identify key components that can potentially be engineered for improvement of crop plants response to the stresses.

发表文章

Publications

1. Zhou Y., Zhang J., Guo G.Q., and Guo Y. 2010. MOM1 is required to prevent aberrant RNA transcriptional read-through in Arabidopsis. Plant Physiology, in press.

2. Xie C.G., Zhou X.N., Deng X.W., and Guo Y. 2010. PKS5, a SNF1-related kinase, interacts with and phosphorylates NPR1, and modulates expression of WRKY38and WRKY62. J. Genet. Genomics 37. In press.

3. Zhou Y., Yang Z.J., Guo G.Q., and Guo Y. 2010. The Microfilament Dynamics Is Required for Root Growth under Alkaline Stress in Arabidopsis. J Integr Plant Biol. In press.

4. Zhang C.G., Guo H.P., Zhang J., Guo G.Q., and Guo Y. 2010. Arabidopsis CSAat1A and CSAat1B Proteins Form a Complex with CULLIN4 and DDB1A and Regulate the Response to UV Irradiation. Plant Cell 22: 2353-2369.

5. Yang Y., Qin Y., Xie C., Zhao F., Liu D., Chen S., Fuglsang A.T., Palmgren M.G., Schumaker K.S., Deng X.W. and Guo Y. 2010. AtJ3 regulates the plasma membrane H⁺-ATPase in Arabidopsis through interaction with the PKS5 kinase.Plant Cell 22:1313-1332.

6. Xie C.G., Lin H., Deng X.W., Guo Y. 2009. Roles of SCaBP8 in salt stress response. Plant Signal Behav. 4(10).

7. Lin H., Yang Y., Quan R., Mendoza I., Wu Y., Du W., Zhao S., Schumaker K.S., Pardo J.M., and Guo Y., 2009. Phosphorylation of SOS3-LIKE CALCIUM BINDING PROTEIN8 by SOS2 Protein Kinase Stabilizes Their Protein Complex and Regulates Salt Tolerance in Arabidopsis. Plant Cell 21: 1607-1619.

8. Gao Y., Gong X., Cao W, Zhao J., Fu L., Wang X., Schumaker K.S, and Guo Y. 2008. SAD2 in Arabidopsis functions in trichome initiation through mediating GL3 function and regulating GL1, TTG1 and GL2 expression. J Integr Plant Biol. 50(7):906-917.

9. Zhao, J.F., Zhang, W.H., Zhao, Y., Gong, X.M., Guo, L., Zhu, G., Wang, X., Gong, Z.Z., Schumaker, K., and Guo, Y. 2007. SAD2, an Importin -Like Protein, Is Required for UV-B Response in Arabidopsis by Mediating MYB4 Nuclear Trafficking. Plant Cell 19(11):3805-3818.

10. Quan, R., Lin, H., Mendoza, I., Zhang, Y., Cao, W., Yang, Y., Shang, M., Chen, S., Pardo, J. M., and Guo, Y. 2007. SCaBP8/CBL10, a Putative Calcium Sensor, Interacts with the Protein Kinase SOS2 to Protect Arabidopsis Shoots from Salt Stress. Plant Cell 19(4):1415-1431.

11. Fuglsang, A., Guo Y., Cuin, T., Qiu, Q., Song, C.-P., Kristiansen, K., Bych, K., Schulz, A., Shabala, S., Schumaker, K., Palmgren, M., and Zhu, J.-K. 2007. Arabidopsis Protein Kinase PKS5 Inhibits the Plasma Membrane H⁺-ATPase by Preventing Interaction with 14-3-3 Protein. Plant Cell 19(5):1617-1634. (Co-first author)

12. Verslues, P.E., Guo, Y., Dong, C.H., Ma, W., and Zhu, J.-K. 2006. Mutation of SAD2, an importin beta-domain protein in Arabidopsis, alters abscisic acid sensitivity. Plant J. 47(5):776-787. (Co-first author)