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影像中心

影像中心

占 成

影像中心主任

电话: 010-80726688-8870

传真: 010-80724500

Room NumberB058

E-mail: zhancheng@nibs.ac.cn

影像中心

北京生命科学研究所影像中心建于2006年,主要提供生物光学成像服务并致力于建立一些新的光学成像技术平台。中心有多套高级光学显微成像系统,包括激光点扫描共聚焦显微镜,转盘式共聚焦显微镜,双光子显微镜,以及宽场荧光显微镜,可以对固定切片、培养细胞和活体动植物细胞等多种生物样品进行光学成像实验。在提供服务的同时,影像中心也致力于开发一些新的光学成像技术,例如多光子活体动物成像和单分子荧光成像,希望将这些技术应用到具体的生物学研究中。

Imaging Facility

The Imaging Facility is a core facility established in 2006, which mainly provides bio-optical imaging services for the institute. Now the facility is equipped with laser point scan confocal, spinning disk confocal, 2-photon microscope and wide field live cell imaging workstation. With theses advanced instruments, the facility can provide imaging solutions for all kinds of biological specimens, including fixed samples, culture cells and in-vivo cellset al. Meanwhile, the facility is developing several imaging techniques, especially 2-photon in vivo imaging and single molecular imaging. We hope to set up new imaging platforms for specific biological questions.

 

发表文章

Publications  

1.

Wang D, He X, Zhao Z, Feng Q, Lin R, Sun Y, Ding T, Xu F#, Luo M#, Zhan C# (2015) Whole-brain mapping of the direct inputs and axonal projections of POMC and AgRP neurons. Frontiers in Neuroanatomy 9:40.

2.

Zhan C*#, Zhou J*, Feng Q, Zhang JE, Lin S, Bao J, Wu P, Luo M#, Acute and long-term suppression of feeding behavior by POMC neurons in the brainstem and hypothalamus, respectively. J Neurosci 33:3624-3632, 2013.

3.

C. Zhan and Luo M, Diverse Patterns of Odor Representation by Neurons in the Anterior Piriform Cortex of Awake Mice. Journal of Neuroscience, 2010, 30(49): 16662-16672

4.

Mengxiao Yu, Fuyou Li,* Zhigang Chen, He Hu, C. Zhan, Hong Yang andChunhui Huang, Laser Scanning Up-Conversion Luminescence Microscopy for Imaging Cells Labeled with Rare-Earth Nanophosphors, Anal. Chem.2009, 81(3), 930–935

5.

Shaoqun Zeng, Xiaohua Lv, Kun Bi, C. Zhan, et al. Analysis of the dispersion compensation of acousto-optic deflectors used for multiphoton imaging. Journal of Biomedical Optics, 2007, 12(2)

6.

X. Lv, C. Zhan, S. Zeng, W. R. Chen, et al. Construction of multiphoton laser scanning microscope based on dual-axis acousto-optic deflector.Review of Scientific Instruments, 2006, 77(4)

7.

S. Zeng, X. Lv, C. Zhan, W. R. Chen, et al. Simultaneous compensation for spatial and temporal dispersion of acousto-optical deflectors for two-dimensional scanning with a single prism. Optics Letters, 2006, 31(8): 1091-1093

 

专利

Patent

Shaoqun Zeng, Qingming Luo, C. Zhan, Xiaohua Lv. LIGHT PULSE POSITIONING WITH DISPERSION COMPENSATION. United States Patent,Patent No: US 7,821,698 B2, Published on Oct.26, 2010