代表文章 Representative Publications
1. Pascolutti R, Erlandson SC,
Burri DJ, Zheng S, Kruse AC* (2020).
Mapping and engineering the interaction between adiponectin and T-cadherin. J Bio Chem. 295 (9), 2749-2759
2. Sjodt M, Rohs PD, Gilman MS,
Erlandson SC, Zheng S, Green AG,
Brock KP, Taguchi A, Kahne D, Walker S, Marks D, Rudner DZ, Bernhardt TG, Kruse
AC* (2020). Structural coordination of polymerization and crosslinking by a
SEDS-bPBP peptidoglycan synthase complex.
Nature Microbiology. 5 (6), 813-820
3. Liu H, Zheng S, Hou X, Liu X, Du K, Lv X, Li Y, Yang F, Li W, Sui J*
(2020). Novel Abs targeting the N-terminus of fibroblast growth factor 19
inhibit hepatocellular carcinoma growth without bile-acid-related side-effects. Cancer science. 111 (5), 1750-1760
4. Zheng S, Abreu N, Levitz
J, Kruse AC* (2019). Structural basis for KCTD-mediated rapid desensitization
of GABAB signaling. Nature. 567: (127-131).
5. Zheng S, Sham LT, Rubino
FA, Brock KP, Robins WP, Mekalanos JJ, Marks DS, Bernhardt TG, Kruse AC*.
(2018) Structural and mutagenic analysis of the lipid II flippase MurJ from
Escherichia coli. Proc. Natl. Acad. Sci.
U.S.A. 115 (26): 6709-6714
6. Sham LT, Zheng S,
Yakhnina AA, Kruse AC, Berhardt TG*. (2018) Loss of specificity variants of
WzxC suggest that substrate recognition is coupled with transporter opening in
MOP-family flippase. Mol Microbiol.109
(5): 633-641
7. Huang P#, Zheng
S#, Wierbowski BM, Kim Y, Nedelcu D, Aravena L, Liu J, Kruse
AC., Salic A*. (2018) The structural basis of smoothened activation in Hedgehog
signaling. Cell 174: 1-13
8. MaMahon C, Baier AS, Pascolutti R, Wegrecki M, Zheng S, Ong JX, Erlandson SC, Hilger
D, Rasmussen SGF, Ring AM, Manglik A*, Kruse AC*.
(2018) Yeast surface display platform for rapid discovery of conformationally
selective nanobodies. Nature Structural
& Molecular Biology. 25: 289-296
9. Zhou D#, Zhu X#, Zheng S, Tan D, Dong MQ, Ye K*. (2018) Cryo-EM structure of an
early precursor of large ribosomal subunit reveals a half-assembled intermediate. Protein Cell. 10 (2): 120-130
10. Sun Q#, Zhu X#, Qi J#, An W#,
Lan P, Tan D, Chen R, Wang B, Zheng S,
Zhang C, Chen X, Zhang W, Chen J, Dong M, Ye K*. (2017) Molecular architecture
of the 90S small subunit pre-ribosome. eLife.
6: e2208
11. Li D, He W, Liu X, Zheng
S, Qi Y, Li H, Mao F, Liu J, Sun Y, Pan L, Du K, Ye K, Li W*, Sui J*.
(2017) A potent human neutralizing antibody Fc-dependently reduces established
HBV infections. eLife. 6: e26738
12. Schmidt HR#, Zheng
S#, Gurpinar E, Koehl A, Manglik A., Kruse AC*. (2016) Crystal
structure of human sigma1 receptor. Nature. 532: 527-530
13. Shen M#, Zhang N#, Zheng S#, Zhang W, Zhang H,
Lu Z, Su Q, Sun Y, Ye K, Li X*. (2016) Calmodulin in complex with the first IQ
motif of myosin-5a functions as an intact calcium sensor. Proc. Natl. Acad. Sci. U.S.A. 113 (40)
14. Zheng S#, Lan P#, Liu X, Ye K*.
(2014) Interaction between Ribosome
Assembly Factors Krr1 and Faf1 Is Essential for Formation of Small
Ribosomal Subunit in Yeast. J
Bio Chem. 289: 22692-703
15. Zheng S, Ye K*. (2014) Purification, crystallization and
preliminary X-ray diffraction
analysis of Imp3 in complex with an Mpp10 peptide
involved in yeast ribosome biogenesis. Acta
Crystallogr F Struct Biol Commun. 70: 918-921
16. Zheng S, Villa R, Wang J, Feng Y,
Wang J, Becker PB, and Ye K*. (2014) Structural basis of X chromosome DNA recognition by MSL2 CXC domain
during dosage compensation in Drosophila. Genes
& Development 28: 2652-2662
17. Zheng S#, Wang J#, Feng Y#*,
Wang J, Ye K*. (2012) Solution structure of MSL2 CXC domain
reveals an unusual Zn3Cys9 cluster and similarity to pre-SET domains of histone lysine methyltransferases. PloS One. 7: e45437
Invited
reviews and comments
1. Zheng S, Kruse AC*. (2019) Ion Channels: Solving a specificity
mystery. eLife
2. Alon A#, Schmidt H#, Zheng S#, Kruse AC*. (2017)
Structure perspectives on Sigma-1 receptor function. Adv Exp Med Biol. 964:5-13