工作经历
Professional Experience
2019年- 北京生命科学研究所高级研究员
2012-2019 北京生命科学研究所研究员
Assistant Investigator, National Institute of Biological Sciences, Beijing, China
2006-2012 美国加州大学旧金山分校解剖发育生物学系,博士后
Postdoctoral Fellow, Dept. of Anatomy and Program in Developmental Biology, University of California, San Francisco, CA, USA
2000-2005 美国加州大学圣地亚哥分校分子病理学系,博士研究生
Graduate Research Assistant in Molecular Pathology, Universityof California, San Diego, CA, USA
1998-2000 美国加州大学圣地亚哥分校细胞及发育生物学系,博士后研究员
Postdoctoral Researcher, Cell and Developmental Biology, Division of Biological Sciences, University of California, San Diego, CA, USA
发表文章
1. Wu H, Yu Y, Huang H, Hu Y, Fu S, Wang Z, Shi M, Zhao X, Yuan J, Li J, Yang X, Bin E, Wei D, Zhang H, Zhang J, Yang C, Cai T, Dai H, Chen J, Tang N. Cell. 2019 Dec 16. pii: S0092-8674(19)31284-X. doi: 10.1016/j.cell.2019.11.027. [Epub ahead of print]
2. Qiqi Chu, ChangfuYao, Xiangbing Qi, Barry Raymond Stripp and Tang N. (2019) STK11 is required for the normal program of ciliated cell differentiation in airways.Cell Discovery.2019 (in press)
3. Van Soldt BJ, Qian J, Li J, Tang N, Lu J, Cardoso WV. (2019) Yap and its subcellular localization have distinct compartment-specific roles in the developing lung.Development. 2019 May 1;146(9).
4. Li J, Tang N. (2018) May the Force Be with You. Dev Cell. 2018 Dec 17;47(6):673-674.
5. Liu L, Lu J, Li X, Wu A, Wu Q, Zhao M, Tang N, Song H. (2018) The LIS1/NDE1 Complex Is Essential for FGF Signaling by Regulating FGF Receptor Intracellular Trafficking. Cell Rep. 2018 Mar 20;22(12):3277-3291.
6. Lin R, Feng Q, Li P, Zhou P, Wang R, Liu Z, Wang Z, Qi X, Tang N, Shao F, Luo M. (2018) A hybridization-chain-reaction-based method for amplifying immunosignals. Nat Methods. 2018 Apr;15(4):275-278.
7. Wang Y, Tang Z, Huang H, Li J, Wang Z, Yu Y, Zhang C, Li J, Dai H, Wang F, Cai T, Tang N . (2018) Pulmonary alveolar type I cell population consists of two distinct subtypes that differ in cell fate. Proc Natl Acad Sci U S A. 2018 Feb 20.
8. Li J, Wang Z, Chu Q, Jiang K, Li J, Tang N. (2018) The Strength of Mechanical Forces Determines the Differentiation of Alveolar Epithelial Cells. Dev Cell. 2018 Feb 5;44(3):297-312.e5.
9. Tang Z, Hu Y, Wang Z, Jiang K, Zhan C, Marshall WF, Tang N. (2018) Mechanical Forces Program the Orientation of Cell Division during Airway Tube Morphogenesis. Dev Cell. 2018 Feb 5; 44, 1-13.
10. Wang Z, Tang N. (2017) The LUNGe to Model Alveolar Lung Diseases in a Dish. Cell Stem Cell. 2017 Oct 5; 21(4): 413-414.
11.Liu Z, Fu S, Tang N. (2017) A Standardized Method for Measuring Internal Lung Surface Area via Mouse Pneumonectomy and Prosthesis Implantation. J Vis Exp. 2017 Jul 26;(125).
12.Liu Z, Wu H, Jiang K, Wang Y, Zhang W, Chu Q, Li J, Huang H, Cai T, Ji H, Yang C, Tang N. (2016) MAPK-mediated YAP activation controls mechanical-tension-induced pulmonary alveolar regeneration. Cell Reports 2016 Aug16; 16(7):1810-9.
13.Tang N., and Marshall WF (2013) Computational analysis of the spatial distribution of mitotic spindle angles in mouse developing airway. Proc. SPIE 8593, 85930N
14.Tang N, Marshall WF (2012) Centrosome Positioning in Vertebrate Development. J Cell Sci Nov. 1; 125: 4951-4961.
15.Tang N, Marshall WF, McMahon M, Metzger RJ, Martin GR (2011) Control of mitotic spindle angle by the RAS-regulated ERK1/2 Pathway determines lung tube shape. Science Jul 15; 333:342-5.
16.Zheng B, Tang T, Tang N, Kudlicka K, Ohtsubo K, Ma P, Marth JD, Farquhar MG and Lehtonen E (2006) Essential role of RGF-PX1/sorting nexin 13 in mouse development and regulation of endocytosis dynamics. Proc Natl Acad Sci U S A Nov 7; 103 (45): 16776-81.
17.Tang N, Mack F, Haase VH, Simon MC and Johnson RS (2006) pVHL function is essential for endothelial extracellular matrix deposition. Mol Cell Biol. Apr; 26(7): 2519-30
18.Mendoza MC, Du F, Iranfar N, Tang N, Ma H, Loomis WF and Firtel RA (2005) Loss of SMEK, a novel, conserved protein, suppresses mek1 null cell polarity, chemotaxis and gene expression defects. Mol Cell Biol. Sep; 25(17):7839-53.
19.Tang N, Wang LC, Esko J, Giodano F, Huang Y, Gerber HP, Ferrara N and Johnson RS (2004) Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis. Cancer Cell Nov; 6(5): 485-95.